Index of disclosure requirements in accordance with art. 964b Swiss Code of Obligations

The following sections comprise the report on non-financial matters in accordance with art. 964b of the Swiss Code of Obligations (the “CO”), which includes an independent practitioner’s limited assurance report on the Sustainability Report 2025. The approval of the report on non-financial matters for the financial year 2025 at the general meeting 2026 is limited to the content of these sections.

Pursuant to art. 964b CO, the report on non-financial matters must cover environmental matters, in particular the CO2 goals, social issues, employee-related issues, respect for human rights, and combating corruption. As part of the materiality analysis, PolyPeptide identified the material sustainability topics, considering their relevance for its business as well as the CO requirements.

Art. 964b CO content requirement

Section

Reference

Article links

 

 

 

 

General information required to understand our business

General information

Page 17

https://report.polypeptide.com/ar/25/en/?p=2971

General information - Basis for preparation

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#basisforpreparation

Management Report 2025 – Strategy

Page 9

https://report.polypeptide.com/ar/25/en/?p=2714

Management Report 2025 – Business Review

Page 13

https://report.polypeptide.com/ar/25/en/?p=2741

 

Stakeholder engagement

Page 26

https://report.polypeptide.com/ar/25/en/?p=2971#stakeholder

Description of the business model

General information

Page 17

https://report.polypeptide.com/ar/25/en/?p=2971

 

Management Report 2025 –Strategy–Business model

Page 9

https://report.polypeptide.com/ar/25/en/?p=2714

Description of materiality assessment

Stakeholder engagement

Page 26

https://report.polypeptide.com/ar/25/en/?p=2971#stakeholder

 

Double materiality assessment

Page 27

https://report.polypeptide.com/ar/25/en/?p=2971#doublematerialityassessment

Description of governance

Governance

Page 19

https://report.polypeptide.com/ar/25/en/?p=2971#governance

Environmental matters (in particular CO2 goals)

Environmental information - Climate change

Page 28

https://report.polypeptide.com/ar/25/en/?p=2972#climatechange

Environmental information - Climate change - Targets and metrics

Page 33

https://report.polypeptide.com/ar/25/en/?p=2972#energy

Environmental information – Pollution

Page 39

https://report.polypeptide.com/ar/25/en/?p=2972#pollution

Environmental information – Resource use and circular economy

Page 43

https://report.polypeptide.com/ar/25/en/?p=2972#resourceuse

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Main impacts, risks and opportunities

Environmental information - Climate change - Impacts, risks and opportunities

Page 29

https://report.polypeptide.com/ar/25/en/?p=2972#ClimateIRO

 

Environmental information - Pollution - Impacts, risks and opportunities

Page 39

https://report.polypeptide.com/ar/25/en/?p=2972#pollution

 

Environmental information - Resources use and circular economy - Impacts, risks and opportunities

Page 43

https://report.polypeptide.com/ar/25/en/?p=2972#resourceuse

 

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Policies adopted, including the due diligence applied

General information - Due diligence across all material topics

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#Duediligence

Environmental information - Climate change - Policies

Page 30

https://report.polypeptide.com/ar/25/en/?p=2972#Climatepolicies

Environmental information - Pollution - Policies

Page 40

https://report.polypeptide.com/ar/25/en/?p=2972#pollutionpolicies

Environmental information - Resource use and circular economy - Policies

Page 44

https://report.polypeptide.com/ar/25/en/?p=2972#resourceusepolicies

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Measures taken to implement policies and assessment of effectiveness

General information - Assessment of effectiveness of measures across material topics

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#effectiveness

 

General information – Governance

Page 19

https://report.polypeptide.com/ar/25/en/?p=2971#governance

 

General information – Strategy and remuneration

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#strategyandremuneration

 

Corporate Governance Report 2025 - 3.7.3 Enterprise Risk Management Framework

Page 116

https://report.polypeptide.com/ar/25/en/?p=2806#enterpriseriskmanagementframework

 

Environmental information – Climate change – Transition plan for climate change mitigation

Page 29

https://report.polypeptide.com/ar/25/en/?p=2972#energy

 

Environmental information – Climate change – Actions

Page 30

https://report.polypeptide.com/ar/25/en/?p=2972#climateactions

 

Environmental information – Pollution – Actions

Page 40

https://report.polypeptide.com/ar/25/en/?p=2972#pollutionactions

 

Environmental information – Resource use and circular economy – Actions

Page 44

https://report.polypeptide.com/ar/25/en/?p=2972#resourceuseactions

 

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Performance indicators

Environmental information – Climate change – Targets and metrics

Page 33

https://report.polypeptide.com/ar/25/en/?p=2972#energy

 

Environmental information – Pollution – Targets and metrics

Page 41

https://report.polypeptide.com/ar/25/en/?p=2972#pollution

 

Environmental information – Resource use and circular economy - Targets and metrics

Page 45

https://report.polypeptide.com/ar/25/en/?p=2972#resourceusetargets

 

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Social issues

Social information - Own workforce

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

 

Social information - Workers in the value chain

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

 

Social information - Access to safe and effective products

Page 57

https://report.polypeptide.com/ar/25/en/?p=2975#accesstosafeandeffectiveproducts

Main impacts, risks and opportunities

Social information - Own workforce - Impacts, risks and opportunities

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

 

Social information - Workers in the value chain - Impacts, risks and opportunities

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

 

Social information - Access to safe and effective products - Impacts, risks and opportunities

Page 57

https://report.polypeptide.com/ar/25/en/?p=2975#accesstosafeandeffectiveproducts

 

Social information - Access to safe and effective products - Processes to remediate negative impacts

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#accessprocessesremediate

Policies adopted, including the due diligence applied

General information - Due diligence across all material topics

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#Duediligence

Social information - Own workforce - Policies

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforcepolicies

Social information - Workers in the value chain - Policies

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainpolicies

Social information - Access to safe and effective products - Policies

Page 57

https://report.polypeptide.com/ar/25/en/?p=2975#Accesspolicies

Measures taken to implement policies and assessment of effectiveness

General information - Assessment of effectiveness of measures across material topics

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#effectiveness

Social information - Own workforce - Processes for engaging with our workforce

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforceprocessesengaging

Social information - Own workforce–Processes to remediate negative impacts and channels for own workforce to raise concerns

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownprocessesremediate

Social information - Own workforce - Actions

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownactions

Social information – Workers in the value chain – Actions

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainactions

Social information – Workers in the value chain – Process for engaging with value chain workers

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainprocesses

Social information – Workers in the value chain – Process to remediate negative impacts and channels for value chain workers to raise concern

Page 56

https://report.polypeptide.com/ar/25/en/?p=2975#valueremediate

Social information – Access to safe and effective products – Processes for engaging with customers

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#accessprocessesengage

Social information – Access to safe and effective products – Processes to remediate negative impacts

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#accessprocessesremediate

Social information – Access to safe and effective products – Actions

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#accesstosafeandeffectiveproducts

 

Social information – Own workforce – Targets and metrics

Page 49

https://report.polypeptide.com/ar/25/en/?p=2975#owntargets

Performance indicators

Social information – Access to safe and effective products – Targets and metrics

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#safetargets

 

Social information – Workers in the value chain – Process for engaging with value chain workers

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainprocesses

 

Social information – Access to safe and effective products – Actions

Page 58

https://report.polypeptide.com/ar/25/en/?p=2975#accessactions

Employee-related issues

Social information - Own workforce

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

Main impacts, risks and opportunities

Social information – Own workforce – Impacts, risks and opportunities

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

Policies adopted, including the due diligence applied

General information - Due diligence across all material topics

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#Duediligence

Social information - Own workforce - Policies

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforcepolicies

Measures taken to implement policies and assessment of effectiveness

General information - Assessment of effectiveness of measures across material topics

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#effectiveness

 

Social information - Own workforce - Processes for engaging with our workforce

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforceprocessesengaging

 

Social information – Own workforce – Processes to remediate negative impacts and channels for own workforce to raise concerns

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownprocessesremediate

 

Social information – Own workforce - Actions

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownactions

Performance indicators

Social information – Own workforce - Targets and metrics

Page 49

https://report.polypeptide.com/ar/25/en/?p=2975#owntargets

Respect for human rights

Social information – Own workforce

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

 

Social information - Workers in the value chain

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

Main impacts, risks and opportunities

Social information – Own workforce – Impacts, risks and opportunities

Page 47

https://report.polypeptide.com/ar/25/en/?p=2975

 

Social information – Workers in the value chain – Impacts, risks and opportunities

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

Policies adopted, including the due diligence applied

General information - Due diligence across all material topics

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#Duediligence

Social information – Own workforce – Policies

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforcepolicies

Social information – Workers in the value chain – Policies

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainpolicies

Measures taken to implement policies and assessment of effectiveness

General information - Assessment of effectiveness of measures across material topics

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#effectiveness

Social information – Own workforce – Processes for engaging with our workforce

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#ownworkforceprocessesengaging

Social information – Own workforce – Processes to remediate negative impacts and channels for own workforce to raise concerns

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownprocessesremediate

Social information – Own workforce – Actions

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownactions

Social information – Workers in the value chain - Actions

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainactions

Social information - Workers in the value chain - Processes for engaging with value chain workers

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainprocesses

Social information - Own workforce–Processes to remediate negative impacts and channels for own workforce to raise concerns

Page 48

https://report.polypeptide.com/ar/25/en/?p=2975#Ownprocessesremediate

 

Social information – Own workforce – Targets and metrics

Page 49

https://report.polypeptide.com/ar/25/en/?p=2975#owntargets

Performance indicators

Social information – Workers in the value chain – Targets and metrics

Page 56

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechaintargets

 

Social information – Workers in the value chain – Process for engaging with value chain workers

Page 55

https://report.polypeptide.com/ar/25/en/?p=2975#Valuechainprocesses

Combating corruption

Governance information - Business conduct

Page 59

https://report.polypeptide.com/ar/25/en/?p=2974

Main impacts, risks and opportunities

Governance information – Business conduct – Impacts, risks and opportunities

Page 59

https://report.polypeptide.com/ar/25/en/?p=2974

Policies adopted, including the due diligence applied

General information - Due diligence across all material topics

Page 22

https://report.polypeptide.com/ar/25/en/?p=2971#Duediligence

Governance information – Business conduct – Policies

Page 59

https://report.polypeptide.com/ar/25/en/?p=2974#Businesspolicies

Measures taken to implement policies and assessment of effectiveness

General information - Assessment of effectiveness of measures across material topics

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#effectiveness

 

Governance information - Business conduct - Actions, prevention and detection of corruption and bribery

Page 60

https://report.polypeptide.com/ar/25/en/?p=2974#businessactions

Performance indicators

Governance information - Business conduct - Targets and metrics

Page 60

https://report.polypeptide.com/ar/25/en/?p=2974#businesstargets

 

Governance information – Business conduct – Incidents of corruption or bribery

Page 61

https://report.polypeptide.com/ar/25/en/?p=2974#busienssinc

References to national, European or international regulations

General information

Page 17

https://report.polypeptide.com/ar/25/en/?p=2974

General information - Basis for preparation

Page 18

https://report.polypeptide.com/ar/25/en/?p=2974#basisforpreparation

GRI content index

Page 77

https://report.polypeptide.com/ar/25/en/?p=2985

Climate disclosures in accordance with art. 964 Swiss Code of Obligations and TCFD recommendations

Page 69

https://report.polypeptide.com/ar/25/en/?p=2976

Coverage of subsidiaries

General information - Basis for preparation

Page 18

https://report.polypeptide.com/ar/25/en/?p=2971#basisforpreparation

Art. 964j-l CO requirements

Section

Reference

Article links

 

 

 

 

PolyPeptide’s due diligence in relation to minerals and metals from conflict-affected areas

Social information - Workers in the value chain

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

PolyPeptide's voluntary report on child labor due diligence in its supply chain

Page 81

https://report.polypeptide.com/ar/25/en/?p=2986

PolyPeptide's due diligence in relation to child labor

Social information - Workers in the value chain

Page 54

https://report.polypeptide.com/ar/25/en/?p=2975#workersinthevaluechain

 

PolyPeptide's voluntary report on child labor due diligence in its supply chain

Page 81

https://report.polypeptide.com/ar/25/en/?p=2986

The report on non-financial matters for the financial year 2025 was approved for publication by the Board of Directors on 10 March 2026, and will be presented to the general meeting of shareholders for approval on 8 April 2026.

Peter Wilden, Chair and Independent
Patrick Aebischer, Vice-Chair and Lead Independent Director
Jane Salik, Independent Member
Erik Schropp, Member
Philippe Weber, Independent Member
Jo LeCouilliard, Independent Member

Baar, 10 March 2026

On behalf of the entire Board of Directors and the Executive Committee,

Peter Wilden

Chair of the Board of Directors

Juan Jose Gonzalez

CEO